International Normalized Ratio Relevance to the Observed Coagulation Abnormalities in Warfarin Treatment and Disseminated Intravascular Coagulation

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Disseminated intravascular coagulation and coagulation disorders.

PURPOSE OF REVIEW An update on recent developments in diagnosis and treatment of disseminated intravascular coagulation. RECENT FINDINGS Disseminated intravascular coagulation is defined as a typical disease condition with laboratory findings indicating massive coagulation activation and reduction in procoagulant capacity. Clinical syndromes associated with the condition are consumption coagu...

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Disseminated Intravascular Coagulation

EVIDENCE DEFINITIONS  Class I: Prospective randomized controlled trial.  Class II: Prospective clinical study or retrospective analysis of reliable data. Includes observational, cohort, prevalence, or case control studies.  Class III: Retrospective study. Includes database or registry reviews, large series of case reports, expert opinion.  Technology assessment: A technology study which doe...

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Disseminated intravascular coagulation.

OBJECTIVES To provide an overview of the pathophysiology, manifestations, diagnosis, and treatment of disseminated intravascular coagulation (DIC) as it occurs in cancer. DATA SOURCES Published articles, research reports, and book chapters. CONCLUSIONS The syndrome of DIC is a serious hypercoagulation state that in its acute form may be life-threatening. The hemorrhage and intravascular coa...

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[Disseminated intravascular coagulation].

The diagnosis of disseminated intravascular coagulation associated with intracranial pathology is discussed. This pathological entity is characterized by a diffuse bleeding diathesis. Laboratory studies suggest a consumption of all clotting and fibrinolytic factors with an elevation of fibrin split products as a sign of the fibrinolytic activity. The treatment consists of the administration of ...

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ژورنال

عنوان ژورنال: Clinical and Applied Thrombosis/Hemostasis

سال: 2018

ISSN: 1076-0296,1938-2723

DOI: 10.1177/1076029618772353